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Balto FAQs

Balto Account​

What is Balto?​

Balto is an AI assistant for Drug Discovery enthusiasts. It uses a chat interface to communicate with users in plain English. Balto is also equipped with Deep Origin’s simulation tools that show superior performance for the toughest industry benchmarks.

How do I sign up for Balto?​

Create your account here and enjoy using Balto!

I did not receive an email confirmation. What should I do?​

Check your spam folder. If the confirmation email is not there, ask to resend the verification email or contact our customer support.

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How do I change the Balto subscription?​

You can go to the billing section in the left panel, select Change Plan and then select a plan that fits your needs.

Balto subscription Change

How many members can I add to my organization?​

Balto Basic allows you to add two additional members to your organization. If you want to add more members to your organization, contact our customer support team.

How do I add members to my organization?​

Select the “Members” menu option on the left panel and click on the “Invite member” button.

add members to my organization

Will my subscription automatically renew?​

Yes, your subscription will automatically renew at the date of your initial sign up date unless you cancel your subscription.

Can I restore my subscription?​

Yes, you can reactivate your account at any time and start where you finished. Please note that your data will be deleted after 90-days of inactivity.

What is your privacy policy?​

General privacy policy is described here.

How do I ask for support?​

You can contact our support team.

Why is it called Balto?​

We named our AI assistant in honor of Balto the sled dog, known for his 1925 emergency supply run of diphtheria antivenom to Nome, Alaska, that saved dozens of lives. We strive for Balto to become similarly helpful and invaluable in drug discovery.

How do I update my profile details?​

Click on settings and select the necessary menu item. You can update the following items:

  • Heading
    • Your name
  • Billing
    • Change your subscription plan
    • Add payment method
    • Add billing address
  • Credits
    • Add credits
  • Members
    • Invite members to your organization
    • Delete members from your organization

profile details

How can I cancel my subscription?​

Please, contact our customer support team if you need to cancel your subscription.

Balto Tiers and Features​

How long is the free trial?​

1 month

What is included in the free trial?​

Free trial includes 50 credits. These many credits are enough to:

  • Dock and find poses for up to 410 molecules
  • Predict up to 910 molecular properties
  • Find novel pockets for up to 10 proteins
  • Analyze up to 305 pages of PDF documents

You can also explore countless free actions such as:

  • Pose overlays and protein visualizations
  • Querying of integrated public databases

What tiers are available?​

Currently, Balto offers only the Basic Tier. Full list of available and upcoming tiers you can find on Balto home page.

How can I request new features?​

We welcome any feature requests with our customer support team. You can also review a list of upcoming features.

Where can I review the full list of current and upcoming Balto features?​

You can review the full list of Balto features in Balto documentation. You can review the list of upcoming features in Balto here.

Does Balto work on a Mobile device?​

Currently, Balto does not work on a mobile device but we are working to make it happen.

Balto Pricing​

I want to use Balto. How do I buy a Balto license?​

Balto uses a subscription-based model with an on-demand, progressive pricing. You can have access to all tools available at the Balto Basic Tier for just $32 per month. Once subscribed, you pay only for algorithms that you use. Democratization of access to molecular modeling tools is one of Deep Origin’s key tenets.

How does on-demand, progressive pricing work in Balto?​

Detailed pricing information can be found here. We use progressive pricing for docking, certain property predictions and analysis of PDF documents. Here are two examples of how progressive pricing work:

Example 1: 5 molecules were submitted for docking

5 molecules x 1.0 credit (Tier 1) = 5.0 credits

Example 2: 100 molecules were submitted for docking

10 molecules x 1.0 credit (Tier 1) + 90 molecules x 0.1 credit (Tier 2) = 19.0 credits

How many credits will I receive with my monthly subscription?​

32 credits

I need more credits to run my simulations. How do I add more credits?​

First, you will need to change your subscription plan from Free Trial to Balto Basic. Then, you click on “credits” balance on the left panel and then “Buy credits” button.

add more credits

What is the difference between paid credits and discount credits?​

Paid credits can be purchased or are automatically allocated at the subscription renewal. Discount credits are released during promotions and the free trial period.

I would like to use a purchase order (PO) instead of a credit card. How do I change it?​

Please, contact our sales team so they can guide you.

Are credits refundable?​

Please, contact our support team if you need to refund your credits.

Balto Functionality​

I signed up for Balto. What should I do next?​

Balto chat provides sample prompts. Feel free to test Balto’s most popular requests yourself.

First Balto step

Alternatively, you can directly ask Balto “I am interested in modeling binding of Gleevec. Where should I start?”

What tasks can Balto execute?​

Full list of Balto features is available in documentation and on the Balto home page. You can also ask Balto directly about its capabilities.

The most popular features are:

  • Docking
  • Finding novel pockets
  • Molecular properties predictions
  • Data retrieval from major public databases
  • Analysis of PDF documents

What algorithms does Balto use for molecular modeling?​

Balto uses Deep Origin’s proprietary algorithms for docking, properties predictions and finding novel pockets. Balto also relies on a few open-source tools and databases such as MolStar, PDB and ChEMBL.

What molecular properties can Balto predict?​

Balto predicts the following properties for credits:

  • Aqueous solubility (LogS)
  • Lipophilicity (LogP and LogD)
  • Likelihood of hERG activity
  • Likelihood of CYP interactions
  • Likelihood of activity in Ames test

Balto predicts the following properties for free:

  • Molecular weight (MW)
  • Protonation
  • Synthetic accessibility score (SAS)
  • Drug-likeness (QED)
  • Functional groups

What databases can Balto query?​

Currently, the list includes PDB, Uniprot, AlphaFold, ChEMBL, BindingDB, and PubChem. We recommend regularly asking Balto about integrated databases as Balto constantly expands accessible knowledge.

What is the size limit for upload files?​

10 Mb

What is the limit on the number of molecules for a single job?​

1,000 molecules

What is the limit on the number of atoms for finding novel pockets with Pocket Finder?​

10,000 atoms

I asked Balto to dock molecules. How do I see the results?​

If you ask Balto to dock 10 molecules or less, Balto will visualize each pose in a separate window.

If the number of molecules is 11 or more, Balto will dock all molecules in the background. You can close the tab, continue with the current chat or start a new one. The results will be uploaded into the Results folder as CSV and SDF files. Just open your file directory, click on refresh (if needed), select files to download and click on download button.

Dock molecules results

How can I upload my molecules for docking?​

You can upload a CSV file containing SMILES of molecules that you want to model. Balto will select SMILES compatible for our docking algorithm, adjust protonation states of the molecules and proceed with docking.

How do I review docked pose?​

You can ask Balto to overlay docked pose and the crystal ligand pose or to overlay different docked poses.

How can I review previous visualizations?​

Scroll to the message that generated the desired visualization and click on “See Details” in the top right corner of that message.

Balto visualizations

I want to share Balto results with my collaborators. How can I do it?​

You can generate a public link and send it to your friends and colleagues for any Balto chat that you created. If users are new to Balto, then Balto will ask the new user to register before showing your chat.

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Does Balto hallucinate?​

Although Balto hallucinations are very rare, it is advisable to verify the information that Balto provides.